U-500 insulin is Public Enemy #1 on the ISMP list. This post dispels the mystery behind concentrated insulin and helps you avoid errors when it comes across your computer screen (or on your NAPLEX)

Pharmacology 101: An Overview of Thiazide Diuretics

In this pharmacology post, tl;dr is going to break down where the salt is in that convoluted distal convoluted tubule so that you know exactly how HCTZ works. You’ll also know what to watch for with this seemingly benign, very cheap, ubiquitous medication, as well as its cousins!

Clinical, Pharmacy School, Practice, ResidencyStephanie KujawskiSeptember 15, 2020thiazide diuretics mechanism, HCTZ vs chlorthalidone, side effects of thiazides, distal convoluted tubule sodium transport

New FDA Approval: Fetroja

Because one can never have too many antibiotics at hand when facing armies of wily bacteria, tl;dr is here to give you the low down on the newest sneaky weapon at hand. Even though this latest cephalosporin makes it increasingly difficult to think in terms of the classic generations, come check out cefiderocol and why it’s extra special in the ID world.

Clinical, FDA Approval, Practice, Pharmacy School, ResidencyStephanie KujawskiSeptember 3, 2020cefiderocol, Fetroja, new cephalosporin antibiotic, medications for resistant bacteria, complicated UTI treatment, carbapenemases resistance treatment, siderophore cephalosporin

Absolute Risk Reduction: Your Secret Weapon in Literature Evaluation

What’s the difference between Absolute Risk and Relative Risk? Quite a lot, actually…

Clinical, Pharmacy School, Practice, ResidencyBrandon DysonAugust 25, 2020Statistics, ARR, NNT, absolute risk reduction, biostats, epidemiology, number needed to treat, stats, how to calculate absolute risk reduction, how to calculate relative risk reduction, absolute risk reduction formula, relative risk reduction formula

Pharmacology 101: An Overview of Statins

Welcome to tl;dr’s first Pharmacology 101 post! In this overview of statins, we review drug information highlights that will help you to remember what makes these medications unique as well as how to counsel patients taking them. So if you (or your patients) like bacon, you probably want to stop by to learn about statins!

Clinical, Pharmacy School, Practice, ResidencyStephanie KujawskiAugust 5, 2020statins LDL HDL, how to treat cholesterol in patients intolerant of statins, statins mechanism of action, adverse effects of statins, statin induced myopathy myalgia rhabdomyolysis, relative statin potency

How to Study for the California Pharmacy Jurisprudence Exam (CPJE)

Is the CPJE coming up in your future? This article will walk you through exactly how to prepare for it to ensure you pass on the first try.

Pharmacy School, Practice, ClinicalBrandon DysonJuly 29, 2020cpje, mpje, california, california pharmacy jurisprudence exam, pharmacy law, controlled substance act, law exam, law test, how to study for the CPJE, how to prepare for the CPJE, what types of questions are on the CPJE, how to pass the CPJE, CPJE study tips, how long to study for the CPJE

Complications of Cirrhosis: Part 3 - Hepatorenal Syndrome

So what’s next in the cascade of complications of cirrhosis? We’ve already discussed portal hypertension as the source of all (liver) evil as well as several complications in Parts 1 and 2, but today tl;dr finally covers hepatorenal syndrome (HRS).

Clinical, Pharmacy School, Practice, ResidencyStephanie KujawskiJuly 21, 2020hepatorenal syndrome treatment, complications of cirrhosis, midodrine octreotide albumin, norepinephrine vs terlipressin

The Total Rundown on Total Parenteral Nutrition

Whether you’re a pharmacy student just encountering your first TPN calculations or a seasoned practitioner who maybe just hasn’t been responsible for nutrition in a hot second, this post is for you. Seriously. SAVOR it. DIGEST it.

Clinical, Pharmacy School, Practice, ResidencyStephanie KujawskiJuly 16, 2020TPN, total parenteral nutrition, how to start TPN, how to calculate TPN, macronutrients, tpn calculation sheet, tpn overview, tpn review, tpn summary

Chemo-Induced Nausea and Vomiting (CINV) in a Nutshell

No matter where you practice, there’s a good chance that you’ll eventually come across CINV. Read this primer to get yourself up to speed.

Clinical, Pharmacy School, Practice, ResidencyBrandon DysonJune 22, 2020CINV primer, cinv, CINV guide, cinv clinical pearls, chemotherapy induced nausea and vomiting, cinv treatment, cinv prevention, cinv physiology, cinv pathophysiology, management of cinv, chemo induced nausea and vomiting prevention, chemo induced nausea and vomiting guidelines, chemo induced nausea and vomiting treatment

Controversy Alert! Use of Aspirin for Primary Prevention

Geez…take off the boxing gloves! We can talk about this like adults, can’t we? It’s just aspirin for primary prevention of cardiovascular disease! Although perhaps saying it’s “just” aspirin doesn’t quite encompass all the drama… I guess we should explain further in this literature-filled post about good old aspirin.

Clinical, Pharmacy School, Practice, ResidencyStephanie KujawskiJune 8, 2020aspirin, primary prevention, heart disease, ASCVD aspirin, ASCVD risk, secondary prevention, cardiovascular disease prevention, heart attack prevention, when to use aspirin, aspirin CV trials, using aspirin for primary prevention, using aspirin for secondary prevention, aspirin primary prevention trials, aspirin secondary prevention trials

Clinical Trials that May Change What You Were Taught in Pharmacy School: Part 2

We’re back with round 2 of clinical trial updates! And this time, we’re tackling the world of infectious diseases. Come investigate what the most recent literature says about topics like sepsis, bacteremia, and cellulitis, and hone your AST brain!

Clinical, Pharmacy School, Practice, ResidencyStephanie KujawskiMay 25, 2020antibiotic updates, antimicrobial stewardship, how to manage sepsis, how long to treat cellulitis, double MRSA coverage, MRSA bacteremia antibiotics, CAMERA-2 trial, DANCE trial, VITAMINS trial, sepsis bundle, surviving sepsis campaign

Everything You Need to Know about Tumor Lysis Syndrome

If you thought learning Chemo Man was all the oncology you’d ever need, guess what…there’s more! Whether you practice (or want to practice) in oncology or you’re in general medicine, baseline knowledge of tumor lysis syndrome is essential. Let tl;dr give you the scoop on this explosive, gotta-know topic!

Clinical, Pharmacy School, Practice, ResidencyStephanie KujawskiMay 10, 2020TLS, what is tumor lysis syndrome, drugs that cause tumor lysis, how to prevent tumor lysis syndrome, treatment of tumor lysis syndrome, uric acid, allopurinol, febuxostat, rasburicase