Posts in Clinical
A Clinician’s Guide to Inpatient Electrolyte Replacement

Your patient is low on electrolytes, so order for them to drink a Gatorade, of course! Tsk, tsk. If only it was that simple… For a topic that seems like basic chemistry, electrolyte replacement is surprisingly daunting. But have no fear, tl;dr is here to give you the rundown on four common electrolyte deficiencies, including recognition and treatment.

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The Ins & Outs of ESBLs

Bacteria are tricky, sneaky buggers. They keep upping the resistance ante, which means we pharmacists have to constantly be on our toes when it comes to choosing appropriate therapies. Come learn about one of the more common resistance mechanisms, the ESBLs, so that you’re prepared to do battle when it reaches your doorstep!

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Diabetic Ketoacidosis: The ABCs of DKA

It’s been a while since we’ve visited a long favorite topic here on tl;dr: diabetes. So in light of the recent addition of a critical care expert to our team, we’re taking advantage of his brain and tasking him with explaining diabetic ketoacidosis (DKA). Come learn how this chronic disease state can lead to an acute, life-threatening situation as well as how you, the pharmacist, can help to manage it.

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What Every Pharmacist Should Know about Drug-Induced (Acquired) Methemoglobinemia

Sure, we at tl;dr obviously like to review the big ticket disease states (heart, kidney, liver, etc). But that doesn’t mean we don’t like delving into the less common issues too! Which is why this week we’re taking you on a journey into methemoglobinemia, a not-so-prevalent-but-oh-so-important-to-pharmacists issue. Come learn one more way to be a pharmacist hero!

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A Pharmacist’s Guide for Adult Gender-Affirming Care

Ever wondered what kinds of non-surgical therapies are available for transgender individuals? How are these patients initiated on therapy and monitored, and is there crossover with medications used for other indications? Don’t worry, you’re not alone if you didn’t learn much (if anything) about this topic in pharmacy school. Tl;dr is here to fill in the gaps so you can better care for all of your patients.

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When Good Drugs Go Bad: Acetaminophen Toxicity

An over-the-counter medication as ubiquitous and readily available as acetaminophen MUST be totally safe, right? Well, not entirely… Come learn how this household name walks a fine line between friend and foe - and also what to do in the event of an overdose.

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An Introduction to Hematopoietic Stem Cell Transplant (HSCT)

We recently covered the basics of hematologic malignancies. But did you know that for some of these patients there is actually an option to try for cure rather than just management? Check out how stem cell transplantation provides patients with an additional treatment strategy. Plus, learn about innovative therapies edging into the stem cell transplant space.

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What Every Pharmacist Should Know about Heparin-Induced Thrombocytopenia

Show of hands… who here has ever been confused as to how a condition characterized by thrombocytopenia could also lead to hypercoagulability and possibly death? Don’t worry, you’re not alone. Let tl;dr break down this not-as-rare-as-we-would-like-it-to-be medication adverse event so that you, too, will be armed and ready to monitor for complications!

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Pharmacology 101: Vasopressors

After more requests over the years than we can count, tl;dr is psyched to finally bring you the one, the only, THE critical care topic… VASOPRESSORS. Sure, they may seem really confusing, but once you understand the pharmacology of the sympathetic nervous system’s receptors, these medications become your best friends.

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A Primer on Hematologic Malignancies for the Non-Oncology Pharmacist

Before you can run, you have to be able to walk. And before you dive into complicated chemotherapy regimens for hematologic malignancies, it sure helps to understand how those malignancies start - which is where tl;dr is here to help! Come learn about blood cell development and where it can go awry.

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Ice, Ice Baby: A Dive into Targeted Temperature Management (TTM)

Have you ever wondered which came first in medicine - science fiction or reality? The topic of therapeutic hypothermia is certainly one that seems like it must have come from a sci fi special, but it’s actually real! Come delve into the literature backing this post-cardiac arrest procedure and see if you think we should continue this chilling practice in the future.

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The Pharmacist's Guide to Chemotherapy-Induced Peripheral Neuropathy

More than likely, you’ve heard of chemotherapy-induced nausea and vomiting. But what are some of the other major side effects of chemo that can significantly impact oncology patients’ quality of life? This week, tl;dr is here to introduce you to another big, bad adverse effect of common cancer treatments - peripheral neuropathy.

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