Ok, so now onto pharmacotherapy - updated for the 2022 Guidelines!

Last time we talked about signs and symptoms and discussed the Frank-Starling curve. We are going to talk about the agents used in HF and how they affect this curve.

Clinical, Residency, PracticeBrandon DysonNovember 12, 2016heart failure, systolic heart failure, diastolic heart failure, HFpEF, HFrEF, HF, CHF, Clinical Pearls, congestive heart failure, cardiovascular, digoxin

Pain Management: The tl;dr Pharmacy Guide

Opioid abuse comes in many forms; and it's not just the stereotypical junkie that's doctor shopping and trying to refill their Norco 2 weeks early "because the cops stole them." Opioid abuse can also show up in more insidious ways.....

Clinical, Pharmacy School, PracticeSamuel OhOctober 13, 2016Clinical Pearls, Pain, Pharmacotherapy, COX-2, NSAIDs, Opioids, Tramadol, Pain Management, Neuropathy, Nociception, opioid conversions, opioid clinical pearls, opioid cheat sheet, pain management, pain management cheat sheet

New FDA Approval: Amjevita

Drug

Adalimumab-atto [Amjevita]

Indication

Amjevita is a biosimilar to adalimumab [Humira], so it has the same indications. It's used in inflammatory conditions mediated by the immune system

FDA Approval, Clinical, Pharmacy School, PracticeBrandon DysonOctober 10, 2016Amjevita, adalimumab, biosimilar, amjevita place in therapy, adalimumab place in therapy

HIV Boot Camp: Entry Inhibitors & Attachment Inhibitors

Well, we're coming full circle here. Our epic series on HIV is nearing its coda. We've only got one "class" of HIV meds left to talk about.

The Entry Inhibitors.

Clinical, Pharmacy School, Practice, ResidencyBrandon DysonSeptember 25, 2016hiv boot camp, entry inhibitor mechanism of action, hiv entry inhibitors, hiv cheat sheet, hiv clinical pearls, maraviroc dosing, enfuvirtide administration, enfuvirtide dosing, maraviroc drug interactions, hiv therapy cheat sheet, entry inhibitor clinical pearls, fusion inhibitor

The Complete (but Practical) Guide to Aminoglycosides

Before we get too far, let’s clarify what drugs fall in the aminoglycoside class. That way we’re all on the same page. When we talk about aminoglycosides, we’re referring to gentamicin, tobramycin, and amikacin.

HIV Boot Camp: Integrase Inhibitors

Integrase Inhibitors (also known as IN Strand Transfer Inhibitors...or commonly abbreviated as INSTIs) first appeared on the market in 2007. This may come as a surprise to you, but their job is to inhibit the HIV enzyme Integrase.

What does Integrase do?

Clinical, Pharmacy School, Practice, ResidencyBrandon DysonSeptember 6, 2016HIV medication dosing, HIV drug cheat sheet, HIV cheat sheet, HIV Clinical pearls, hiv therapy cheat sheet, HIV clinical pearls, HIV drugs cheat sheet, HAART cheat sheet, HAART, integrase inhibitors, dolutegravir, Triumeq, elvitegravir, raltegravir

Making Sense of Monoclonal Antibodies

Hello all. I've written another article for Pharmacy Times. We've written about monoclonal antibodies previously (here, and here)..but this is a more "consolidated" and coherent article on the subject.

You can check it out here:

Clinical, Pharmacy School, Practice, ResidencyBrandon DysonAugust 31, 2016pharmacy times, monoclonal antibody guide, monoclonal antibodies made simple, monoclonal antibodies, monoclonal antibody clinical pearls, monoclonal antibody nomenclature, mabs, -mab

HIV Boot Camp: PIs

PIs. Ahhh the ever-so-important private investigators.

Err...I mean protease inhibitors.

You may recall that we've already discussed protease inhibitors in our post on Hepatitis C.

Apixaban use in Hemodialysis?

Howdy all. This is just a quick note to let you know that I wrote a short piece for Pharmacy Times.

You can check it out here:

Clinical, Pharmacy School, Practice, ResidencyBrandon DysonAugust 26, 2016apixaban, hemodialysis, pharmacy times, literature evaluation, HD, dialysis, anticoagulation

Acid - Base Disorders: Essentials for Pharmacists

I have a confession to make...

I didn't "get" acid-base disorders until well after pharmacy school. They were something I was willing to skate through. To take an "L" on the exam if I had to.

HIV Boot Camp: NNRTIs

Non-Nucleoside Reverse Transcriptase Inhibitors, or NNRTIs (pronounced like NRTIs, but with a stutter), are the next class of HIV drugs we will be covering.

What makes a NON-nucleoside as opposed to a regular old fashioned nucleoside reverse transcriptase inhibitor?

The Ultimate Guide to Oncology Pharmacy for the Non-Oncologist

Oncology pharmacy is hard.

Like, really hard.

You get a 3 - 5 week module during school. Maybe you have an APPE rotation. But there's just too much. Too many types of cancers. Too much history that explains how we got to where we are.

Clinical, Pharmacy School, Practice, ResidencyBrandon DysonJuly 31, 2016oncology, oncology pharmacy, cinv, ESA, G-CSF, GM-CSF, chemotherapy, Monoclonal Antibodies, -mab, tyrosine kinase inhibitor, TKI, neutropenic fever, febrile neutropenia, chemotherapy cheat sheet, hypercalcemia of malignancy, tumor lysis syndrome, colony stimulating factors, cytotoxic, chemo, cancer, oncology clinical pearls, chemotherapy clinical pearls, chemotherapy induced nausea and vomiting, cinv clinical pearls, cancer clinical pearls, erythropoietin stimulating agents, ESA APPRISE, platelet stimulating agents, infusion reaction, Anticoagulation, anticoagulation in cancer patients, tyrosine kinase inhibitor clinical pearls, monoclonal antibody clinical pearls, carboplatin, carboplatin dosing, the calvert formula, dose limiting toxicity, oncology cheat sheet, targeted therapy cheat sheet, chemo cheat sheet