Editor's Note: It is with great pleasure that I introduce Nina Vadiei, PharmD. Nina is a totally bad ass PGY2 Psych Pharmacy Resident who has written the excellent post you're about to read. She's sort of like a wizard when it comes to all things 'psych,' and we really appreciate her dropping knowledge bombs here for you all.
Pro Tip: There is a whole bunch of awesome dosing charts at the end of this post.
Read Moresofosbuvir / velpatasvir [Epclusa]
Epclusa is used for treatment of chronic hepatitis C (HCV). It can be used in patients both with and without cirrhosis. If the patient does have cirrhosis (moderate to severe), Epclusa should be given with ribavirin.
Eplcusa can be given all by its lonesome self if there is no cirrhosis or if cirrhosis is in earlier stages.
Read MoreHypertension has been called the “silent killer.” It’s basically asymptomatic unless your blood pressure is high enough to classify as a "hypertensive urgency/emergency." Only then do you really notice anything. You'll get headaches, dizziness, blurry vision, shortness of breath...that sort of thing.
Otherwise, a hypertensive patient feels normal. But behind the scenes, bad stuff is going down in the body.
Read MoreNucleoside Reverse Transcriptase Inhibitors make up what's called the "backbone" of every traditional HAART regimen. It is also an awfully long phrase to type, so I will refer to them only as "NRTIs" from here on out.
But before I go on, there's another distinction I have to make. There are actually both nucleoside and nucelotide reverse transcriptase inhibitors. We lump them into the same "NRTI" bucket because they work in exactly the same way. But they are technically different from each other.
Read MoreEditor's Note: She's baaaaaaacccckkk... Stephanie Kujawski, PharmD, BCPS is back with the next installment in her epic series: Pharmacokinetics Dosing Wars. Up for today, we have Episode II: Attack of the Vancomycin. It seems that our hero, Han Solo, has contracted a nasty MRSA infection (which apparently you can do while being frozen in carbonite).
Read MoreWhen I was finishing up pharmacy school (2013), the landscape of Hep-C therapy was drastically changing. Two new drugs, boceprevir and telaprevir, were fresh on the market and were "game changers" according to any and everyone. In fact--I presented these new protease inhibitors (in all their majesty) during my residency interviews.
Now it's 2016 and they're both gone.
Read MoreEditor's note: To date, our most reader requested topic has been HIV. We've written a guest post at MedEd101 to cover the most NAPLEX-worthy testing points. But we thought we'd dig in a little further here. Over the next few weeks, we're posting a series called HIV Boot Camp. We'll shore up your HIV fundamentals. Then we'll breakdown each drug class piece by piece to highlight what you need to know. For convenience, we'll link each part of the series here. Part I
Part II: Treatment Goals and Considerations
Alright. Last time we looked at the background and pathophysiology of HIV. We looked at a small glimpse of what a patient might experience in the early days of an HIV infection. As practitioners, we have to ask ourselves "Now what?" Is it time to just give the patient an Atripla and go on about our day?
Read MoreSo, you’re a second year pharmacy student sitting in pharmacokinetics class. You're listening to your professor animatedly discuss this strange new topic. But let’s be honest, you’re still trying to figure out what the word "pharmacokinetics" (or even regular "kinetics") means.
Frankly, you’re just excited to have a new super long word to use when playing hangman with your classmates.
Read MoreEditor's note: To date, our most reader requested topic has been HIV. We've written a guest post at MedEd101 to cover the most NAPLEX-worthy testing points. But we thought we'd dig in a little further here. Over the next few weeks, we're posting a series called HIV Boot Camp. We'll shore up your HIV fundamentals. Then we'll breakdown each drug class piece by piece to highlight what you need to know. For convenience, we'll link each part of the series here.
Background
HIV is a bastard. Let's just start right out with that
Read MorePimavenserin [Nuplazid]
The treatment of hallucinations and delusions associated with psychosis in Parkinson's Disease
Read MoreReslizumab [Cinqair]
It's yet another monoclonal antibody (YAMA? #YAMA?) approved for the treatment of severe asthma that is poorly controlled.
Read MoreIt is a truth universally acknowledged, that a doctor in possession of a cellulitis patient, must be in want of an antibiotic recommendation from pharmacy....
Once, a medical resident called me to ask about a patient on the floor I was covering. The patient was 23, and in good health. He showed up to the ED overnight because of a worsening red/swollen wound he received doing construction work a few days prior. He was afebrile.
The overnight team admitted him to the hospital and started on Vanc and Zosyn (I like to call it "ZoVan").
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